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Development of a High-Efficacy Reprogramming Method for Generating Human Induced Pluripotent Stem (iPS) Cells from Pathologic and Senescent Somatic Cells

Induced pluripotent stem (iPS) cells are a type of artificial pluripotent stem cell induced by the epigenetic silencing of somatic cells by the Yamanaka factors. Advances in iPS cell reprogramming technology will allow aging or damaged cells to be replaced by a patient’s own rejuvenated cells. Howev...

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Detalles Bibliográficos
Autores principales: Tanaka, Naomichi, Kato, Hidemasa, Tsuda, Hiromi, Sato, Yasunori, Muramatsu, Toshihiro, Iguchi, Atsushi, Nakajima, Hiroyuki, Yoshitake, Akihiro, Senbonmatsu, Takaaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555779/
https://www.ncbi.nlm.nih.gov/pubmed/32942642
http://dx.doi.org/10.3390/ijms21186764