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Deoxypodophyllotoxin, a Lignan from Anthriscus sylvestris, Induces Apoptosis and Cell Cycle Arrest by Inhibiting the EGFR Signaling Pathways in Esophageal Squamous Cell Carcinoma Cells

Deoxypodophyllotoxin (DPT) derived from Anthriscus sylvestris (L.) Hoffm has attracted considerable interest in recent years because of its anti-inflammatory, antitumor, and antiviral activity. However, the mechanisms underlying DPT mediated antitumor activity have yet to be fully elucidated in esop...

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Detalles Bibliográficos
Autores principales: Kwak, Ah-Won, Lee, Mee-Hyun, Yoon, Goo, Cho, Seung-Sik, Choi, Joon-Seok, Chae, Jung-Il, Shim, Jung-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555783/
https://www.ncbi.nlm.nih.gov/pubmed/32961992
http://dx.doi.org/10.3390/ijms21186854