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Ameliorative Properties of Boronic Compounds in In Vitro and In Vivo Models of Alzheimer’s Disease

Alzheimer’s disease (AD) is characterized by amyloid (Aβ) aggregation, hyperphosphorylated tau, neuroinflammation, and severe memory deficits. Reports that certain boronic compounds can reduce amyloid accumulation and neuroinflammation prompted us to compare trans-2-phenyl-vinyl-boronic-acid-MIDA-es...

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Detalles Bibliográficos
Autores principales: Maiti, Panchanan, Manna, Jayeeta, Burch, Zoe N., Flaherty, Denise B., Larkin, Joseph D., Dunbar, Gary L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555802/
https://www.ncbi.nlm.nih.gov/pubmed/32933008
http://dx.doi.org/10.3390/ijms21186664