Myelosuppression in Patients Treated with the Telomerase Inhibitor Imetelstat Is Not Mediated through Activation of Toll-Like Receptors

Imetelstat sodium (GRN163L; hereafter, imetelstat) is a first-in-class telomerase inhibitor that has demonstrated activity in patients with myeloproliferative neoplasms (MPNs). Treatment with imetelstat has been associated with thrombocytopenia and other hematologic adverse effects that were managea...

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Detalles Bibliográficos
Autores principales: Baerlocher, Gabriela M., Rusbuldt, Joshua, Bussolari, Jacqueline, Huang, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555816/
https://www.ncbi.nlm.nih.gov/pubmed/32911605
http://dx.doi.org/10.3390/ijms21186550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555816/
https://www.ncbi.nlm.nih.gov/pubmed/32911605
http://dx.doi.org/10.3390/ijms21186550

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