Mismatch-Repair Protein Expression in High-Grade Gliomas: A Large Retrospective Multicenter Study

Background: DNA mismatch repair (MMR) is a system for repairing errors in DNA replication. Cancer cells with MMR deficiency can have immunohistochemical loss of MMR protein expression leading to a hypermutable phenotype that may correlate with anti-PD1 efficacy. Scant data exist about immunohistoche...

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Detalles Bibliográficos
Autores principales: Caccese, Mario, Ius, Tamara, Simonelli, Matteo, Fassan, Matteo, Cesselli, Daniela, Dipasquale, Angelo, Cavallin, Francesco, Padovan, Marta, Salvalaggio, Alessandro, Gardiman, Marina Paola, Skrap, Miran, Zagonel, Vittorina, Lombardi, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555820/
https://www.ncbi.nlm.nih.gov/pubmed/32937743
http://dx.doi.org/10.3390/ijms21186716

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555820/
https://www.ncbi.nlm.nih.gov/pubmed/32937743
http://dx.doi.org/10.3390/ijms21186716

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