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Mismatch-Repair Protein Expression in High-Grade Gliomas: A Large Retrospective Multicenter Study
Background: DNA mismatch repair (MMR) is a system for repairing errors in DNA replication. Cancer cells with MMR deficiency can have immunohistochemical loss of MMR protein expression leading to a hypermutable phenotype that may correlate with anti-PD1 efficacy. Scant data exist about immunohistoche...
Autores principales: | Caccese, Mario, Ius, Tamara, Simonelli, Matteo, Fassan, Matteo, Cesselli, Daniela, Dipasquale, Angelo, Cavallin, Francesco, Padovan, Marta, Salvalaggio, Alessandro, Gardiman, Marina Paola, Skrap, Miran, Zagonel, Vittorina, Lombardi, Giuseppe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555820/ https://www.ncbi.nlm.nih.gov/pubmed/32937743 http://dx.doi.org/10.3390/ijms21186716 |
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