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Systemic Oxidative Stress and Visceral Adipose Tissue Mediators of NLRP3 Inflammasome and Autophagy Are Reduced in Obese Type 2 Diabetic Patients Treated with Metformin

Obesity is a low-grade inflammatory condition affecting a range of individuals, from metabolically healthy obese (MHO) subjects to type 2 diabetes (T2D) patients. Metformin has been shown to display anti-inflammatory properties, though the underlying molecular mechanisms are unclear. To study whethe...

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Detalles Bibliográficos
Autores principales: Abad-Jiménez, Zaida, López-Domènech, Sandra, Díaz-Rúa, Rubén, Iannantuoni, Francesca, Gómez-Abril, Segundo Ángel, Periañez-Gómez, Dolores, Morillas, Carlos, Víctor, Víctor M., Rocha, Milagros
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555880/
https://www.ncbi.nlm.nih.gov/pubmed/32967076
http://dx.doi.org/10.3390/antiox9090892