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Methrotexate Treatment Inmunomodulates Abnormal Cytokine Expression by T CD4 Lymphocytes Present in DMARD-Naïve Rheumatoid Arthritis Patients

CD4(+)T-lymphocytes are relevant in the pathogenesis of rheumatoid arthritis (RA), however, their potential involvement in early RA remains elusive. Methotrexate (MTX) is a commonly used disease-modifying antirheumatic drug (DMARD), but its mechanism has not been fully established. In 47 new-onset D...

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Detalles Bibliográficos
Autores principales: Monserrat Sanz, Jorge, Bohórquez, Cristina, Gómez, Ana Maria, Movasat, Atusa, Pérez, Ana, Ruíz, Lucía, Diaz, David, Sánchez, Ana Isabel, Albarrán, Fernando, Sanz, Ignacio, Álvarez-Mon, Melchor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555887/
https://www.ncbi.nlm.nih.gov/pubmed/32961930
http://dx.doi.org/10.3390/ijms21186847