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Oxidative Oligomerization of DBL Catechol, a Potential Cytotoxic Compound for Melanocytes, Reveals the Occurrence of Novel Ionic Diels-Alder Type Additions

The exposure of human skin to 4-(4-hydroxyphenyl)-2-butanone (raspberry ketone, RK) is known to cause chemical/occupational leukoderma. RK is a carbonyl derivative of 4-(4-hydroxyphenyl)-2-butanol (rhododendrol), a skin whitening agent that was found to cause leukoderma in skin of many consumers. Th...

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Detalles Bibliográficos
Autores principales: Sugumaran, Manickam, Umit, Kubra, Evans, Jason, Muriph, Rachel, Ito, Shosuke, Wakamatsu, Kazumasa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555913/
https://www.ncbi.nlm.nih.gov/pubmed/32942764
http://dx.doi.org/10.3390/ijms21186774