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New Factors Enhancing the Reactivity of Cysteines in Molten Globule-Like Structures

Protein cysteines often play crucial functional and structural roles, so they are emerging targets to design covalent thiol ligands that are able to modulate enzyme or protein functions. Some of these residues, especially those involved in enzyme mechanisms—including nucleophilic and reductive catal...

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Detalles Bibliográficos
Autores principales: Gambardella, Giorgia, Cattani, Giada, Bocedi, Alessio, Ricci, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555924/
https://www.ncbi.nlm.nih.gov/pubmed/32971812
http://dx.doi.org/10.3390/ijms21186949