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Specific miRNA and Gene Deregulation Characterize the Increased Angiogenic Remodeling of Thoracic Aneurysmatic Aortopathy in Marfan Syndrome

Marfan syndrome (MFS) is a connective tissue disease caused by mutations in the FBN1 gene, leading to alterations in the extracellular matrix microfibril assembly and the early formation of thoracic aorta aneurysms (TAAs). Non-genetic TAAs share many clinico-pathological aspects with MFS and deregul...

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Detalles Bibliográficos
Autores principales: D’Amico, Federico, Doldo, Elena, Pisano, Calogera, Scioli, Maria Giovanna, Centofanti, Federica, Proietti, Giulia, Falconi, Mattia, Sangiuolo, Federica, Ferlosio, Amedeo, Ruvolo, Giovanni, Orlandi, Augusto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555983/
https://www.ncbi.nlm.nih.gov/pubmed/32961817
http://dx.doi.org/10.3390/ijms21186886