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Ribosome Pausing at Inefficient Codons at the End of the Replicase Coding Region Is Important for Hepatitis C Virus Genome Replication

Hepatitis C virus (HCV) infects liver cells and often causes chronic infection, also leading to liver cirrhosis and cancer. In the cytoplasm, the viral structural and non-structural (NS) proteins are directly translated from the plus strand HCV RNA genome. The viral proteins NS3 to NS5B proteins con...

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Detalles Bibliográficos
Autores principales: Gerresheim, Gesche K., Hess, Carolin S., Shalamova, Lyudmila A., Fricke, Markus, Marz, Manja, Andreev, Dmitri E., Shatsky, Ivan N., Niepmann, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555993/
https://www.ncbi.nlm.nih.gov/pubmed/32971876
http://dx.doi.org/10.3390/ijms21186955