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Ribosome Pausing at Inefficient Codons at the End of the Replicase Coding Region Is Important for Hepatitis C Virus Genome Replication
Hepatitis C virus (HCV) infects liver cells and often causes chronic infection, also leading to liver cirrhosis and cancer. In the cytoplasm, the viral structural and non-structural (NS) proteins are directly translated from the plus strand HCV RNA genome. The viral proteins NS3 to NS5B proteins con...
Autores principales: | Gerresheim, Gesche K., Hess, Carolin S., Shalamova, Lyudmila A., Fricke, Markus, Marz, Manja, Andreev, Dmitri E., Shatsky, Ivan N., Niepmann, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7555993/ https://www.ncbi.nlm.nih.gov/pubmed/32971876 http://dx.doi.org/10.3390/ijms21186955 |
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