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Oxymatrine exerts anti-fibrotic effects in a rat model of hepatic fibrosis by suppressing endoplasmic reticulum stress

OBJECTIVE: This study evaluated the anti-fibrotic effects of oxymatrine and the role of endoplasmic reticulum (ER) stress in hepatic fibrosis (HF) in animal models. METHODS: The HF rat model was established by exposure to NaAsO(2), followed by treatment with oxymatrine. Biomarkers of HF and ER stres...

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Detalles Bibliográficos
Autores principales: Liu, Xiaodong, Wang, Dong, Yang, Wenping, Wu, Xiaomeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556176/
https://www.ncbi.nlm.nih.gov/pubmed/33044865
http://dx.doi.org/10.1177/0300060520961681