GC1qR Cleavage by Caspase-1 Drives Aerobic Glycolysis in Tumor Cells

Self-sustained cell proliferation constitutes one hallmark of cancer enabled by aerobic glycolysis which is characterized by imbalanced glycolysis and mitochondrial oxidative phosphorylation (OXPHOS) activity, named the Warburg effect. The C1q binding protein (C1QBP; gC1qR) is pivotal for mitochondr...

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Detalles Bibliográficos
Autores principales: Sünderhauf, Annika, Raschdorf, Annika, Hicken, Maren, Schlichting, Heidi, Fetzer, Franziska, Brethack, Ann-Kathrin, Perner, Sven, Kemper, Claudia, Ghebrehiwet, Berhane, Sina, Christian, Derer, Stefanie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556196/
https://www.ncbi.nlm.nih.gov/pubmed/33102234
http://dx.doi.org/10.3389/fonc.2020.575854

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556196/
https://www.ncbi.nlm.nih.gov/pubmed/33102234
http://dx.doi.org/10.3389/fonc.2020.575854

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