Mitochondrial Energy-Regulating Effect of Atractyloside Inhibits Hepatocellular Steatosis Through the Activation of Autophagy

BACKGROUND AND AIM: Atractyloside (ATR), a mitochondrial uncoupler, is known for its specific inhibition of mitochondrial oxidative phosphorylation. Previous studies have reported that moderate mitochondrial uncoupling effect is beneficial to increase the decomposition and clearance of hepatic lipid...

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Detalles Bibliográficos
Autores principales: Zhang, Pengfei, Li, Lijun, Sun, Huimin, Zhang, Yipeng, Zhang, Guoliang, Zhang, Tianyu, Zeng, Changchun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556285/
https://www.ncbi.nlm.nih.gov/pubmed/33101031
http://dx.doi.org/10.3389/fphar.2020.575695

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556285/
https://www.ncbi.nlm.nih.gov/pubmed/33101031
http://dx.doi.org/10.3389/fphar.2020.575695

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