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AMP-independent activator of AMPK for treatment of mitochondrial disorders

Mitochondrial diseases are a clinically heterogenous group of disorders caused by respiratory chain dysfunction and associated with progressive, multi-systemic phenotype. There is no effective treatment or cure, and no FDA-approved drug for treating mitochondrial disease. To identify and characteriz...

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Detalles Bibliográficos
Autores principales: Moore, Tereza, Yanes, Rolando E., Calton, Melissa A., Vollrath, Douglas, Enns, Gregory M., Cowan, Tina M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556449/
https://www.ncbi.nlm.nih.gov/pubmed/33052980
http://dx.doi.org/10.1371/journal.pone.0240517