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The molecular basis for the prothrombotic state in sickle cell disease
The genetic and molecular basis of sickle cell disease (SCD) has long been characterized but the pathophysiological basis has not been entirely defined. How a red cell hemolytic disorder initiates inflammation, endothelial dysfunction, coagulation activation, and eventually leads to vascular thrombo...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556662/ https://www.ncbi.nlm.nih.gov/pubmed/33054077 http://dx.doi.org/10.3324/haematol.2019.239350 |