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Thromboinflammatory mechanisms in sickle cell disease – challenging the hemostatic balance

Sickle cell disease (SCD) is an inherited hemoglobinopathy that is caused by the presence of abnormal hemoglobin S (HbS) in red blood cells, leading to alterations in red cell properties and shape, as the result of HbS dexoygenation and subsequent polymerization. The pathophysiology of SCD is charac...

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Detalles Bibliográficos
Autores principales: Conran, Nicola, De Paula, Erich V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556678/
https://www.ncbi.nlm.nih.gov/pubmed/33054078
http://dx.doi.org/10.3324/haematol.2019.239343