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Thromboinflammatory mechanisms in sickle cell disease – challenging the hemostatic balance
Sickle cell disease (SCD) is an inherited hemoglobinopathy that is caused by the presence of abnormal hemoglobin S (HbS) in red blood cells, leading to alterations in red cell properties and shape, as the result of HbS dexoygenation and subsequent polymerization. The pathophysiology of SCD is charac...
Autores principales: | Conran, Nicola, De Paula, Erich V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Fondazione Ferrata Storti
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556678/ https://www.ncbi.nlm.nih.gov/pubmed/33054078 http://dx.doi.org/10.3324/haematol.2019.239343 |
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