Humanized zebrafish enhance human hematopoietic stem cell survival and promote acute myeloid leukemia clonal diversity

Xenograft models are invaluable tools in establishing the current paradigms of hematopoiesis and leukemogenesis. The zebrafish has emerged as a robust alternative xenograft model but, like mice, lacks specific cytokines that mimic the microenvironment found in human patients. To address this critica...

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Detalles Bibliográficos
Autores principales: Rajan, Vinothkumar, Melong, Nicole, Wong, Wing Hing, King, Benjamin, Tong, R. Spencer, Mahajan, Nitin, Gaston, Daniel, Lund, Troy, Rittenberg, David, Dellaire, Graham, Campbell, Clinton J.V., Druley, Todd, Berman, Jason N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Fondazione Ferrata Storti 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556680/
https://www.ncbi.nlm.nih.gov/pubmed/33054079
http://dx.doi.org/10.3324/haematol.2019.223040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556680/
https://www.ncbi.nlm.nih.gov/pubmed/33054079
http://dx.doi.org/10.3324/haematol.2019.223040

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