Single-cell dynamics of pannexin-1-facilitated programmed ATP loss during apoptosis

ATP is essential for all living cells. However, how dead cells lose ATP has not been well investigated. In this study, we developed new FRET biosensors for dual imaging of intracellular ATP level and caspase-3 activity in single apoptotic cultured human cells. We show that the cytosolic ATP level st...

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Detalles Bibliográficos
Autores principales: Imamura, Hiromi, Sakamoto, Shuichiro, Yoshida, Tomoki, Matsui, Yusuke, Penuela, Silvia, Laird, Dale W, Mizukami, Shin, Kikuchi, Kazuya, Kakizuka, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556867/
https://www.ncbi.nlm.nih.gov/pubmed/33052098
http://dx.doi.org/10.7554/eLife.61960

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556867/
https://www.ncbi.nlm.nih.gov/pubmed/33052098
http://dx.doi.org/10.7554/eLife.61960

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