Sperm-specific COX6B2 enhances oxidative phosphorylation, proliferation, and survival in human lung adenocarcinoma

Cancer testis antigens (CTAs) are proteins whose expression is normally restricted to the testis but anomalously activated in human cancer. In sperm, a number of CTAs support energy generation, however, whether they contribute to tumor metabolism is not understood. We describe human COX6B2, a compon...

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Detalles Bibliográficos
Autores principales: Cheng, Chun-Chun, Wooten, Joshua, Gibbs, Zane A, McGlynn, Kathleen, Mishra, Prashant, Whitehurst, Angelique W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556868/
https://www.ncbi.nlm.nih.gov/pubmed/32990599
http://dx.doi.org/10.7554/eLife.58108

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556868/
https://www.ncbi.nlm.nih.gov/pubmed/32990599
http://dx.doi.org/10.7554/eLife.58108

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