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Dissociable control of unconditioned responses and associative fear learning by parabrachial CGRP neurons

Parabrachial CGRP neurons receive diverse threat-related signals and contribute to multiple phases of adaptive threat responses in mice, with their inactivation attenuating both unconditioned behavioral responses to somatic pain and fear-memory formation. Because CGRP(PBN) neurons respond broadly to...

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Detalles Bibliográficos
Autores principales: Bowen, Anna J, Chen, Jane Y, Huang, Y Waterlily, Baertsch, Nathan A, Park, Sekun, Palmiter, Richard D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556873/
https://www.ncbi.nlm.nih.gov/pubmed/32856589
http://dx.doi.org/10.7554/eLife.59799