Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks

Despite a common understanding that Gli TFs are utilized to convey a Hh morphogen gradient, genetic analyses suggest craniofacial development does not completely fit this paradigm. Using the mouse model (Mus musculus), we demonstrated that rather than being driven by a Hh threshold, robust Gli3 tran...

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Detalles Bibliográficos
Autores principales: Elliott, Kelsey H, Chen, Xiaoting, Salomone, Joseph, Chaturvedi, Praneet, Schultz, Preston A, Balchand, Sai K, Servetas, Jeffrey D, Zuniga, Aimée, Zeller, Rolf, Gebelein, Brian, Weirauch, Matthew T, Peterson, Kevin A, Brugmann, Samantha A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556880/
https://www.ncbi.nlm.nih.gov/pubmed/33006313
http://dx.doi.org/10.7554/eLife.56450

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556880/
https://www.ncbi.nlm.nih.gov/pubmed/33006313
http://dx.doi.org/10.7554/eLife.56450

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