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Rebelled epigenome: histone H3S10 phosphorylation and H3S10 kinases in cancer biology and therapy
BACKGROUND: With the discovery that more than half of human cancers harbor mutations in chromatin proteins, deregulation of epigenetic mechanisms has been recognized a hallmark of malignant transformation. Post-translational modifications (PTMs) of histone proteins, as main components of epigenetic...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556946/ https://www.ncbi.nlm.nih.gov/pubmed/33054831 http://dx.doi.org/10.1186/s13148-020-00941-2 |