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Rebelled epigenome: histone H3S10 phosphorylation and H3S10 kinases in cancer biology and therapy

BACKGROUND: With the discovery that more than half of human cancers harbor mutations in chromatin proteins, deregulation of epigenetic mechanisms has been recognized a hallmark of malignant transformation. Post-translational modifications (PTMs) of histone proteins, as main components of epigenetic...

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Detalles Bibliográficos
Autores principales: Komar, Dorota, Juszczynski, Przemyslaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556946/
https://www.ncbi.nlm.nih.gov/pubmed/33054831
http://dx.doi.org/10.1186/s13148-020-00941-2