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PET imaging of P2X(7)R in the experimental autoimmune encephalomyelitis model of multiple sclerosis using [(11)C]SMW139

BACKGROUND: Non-invasive imaging of the activation status of microglia and the ability to identify a pro- or anti-inflammatory environment can provide valuable insights not only into pathogenesis of neuro-inflammatory and neurodegenerative diseases but also the monitoring of the efficacy of immunomo...

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Detalles Bibliográficos
Autores principales: Beaino, Wissam, Janssen, Bieneke, Kooijman, Esther, Vos, Ricardo, Schuit, Robert C., O’Brien-Brown, James, Kassiou, Michael, van het Hof, Bert, Vugts, Danielle J., de Vries, Helga E., Windhorst, Albert D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556947/
https://www.ncbi.nlm.nih.gov/pubmed/33054803
http://dx.doi.org/10.1186/s12974-020-01962-7