Ribosome profiling in mouse hippocampus: plasticity-induced regulation and bidirectional control by TSC2 and FMRP

BACKGROUND: Mutations in TSC2 are the most common cause of tuberous sclerosis (TSC), a disorder with a high incidence of autism and intellectual disability. TSC2 regulates mRNA translation required for group 1 metabotropic glutamate receptor-dependent synaptic long-term depression (mGluR-LTD) and be...

Descripción completa

Detalles Bibliográficos
Autores principales: Hien, Annie, Molinaro, Gemma, Liu, Botao, Huber, Kimberly M., Richter, Joel D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556950/
https://www.ncbi.nlm.nih.gov/pubmed/33054857
http://dx.doi.org/10.1186/s13229-020-00384-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556950/
https://www.ncbi.nlm.nih.gov/pubmed/33054857
http://dx.doi.org/10.1186/s13229-020-00384-9

Ejemplares similares