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AAV9-Retro mediates efficient transduction with axon terminal absorption and blood–brain barrier transportation

Recombinant adeno-associated viruses (rAAVs), particularly those that permit efficient gene transfer to neurons from axonal terminals or across the blood–brain barrier, are useful vehicles for structural and functional studies of the neural circuit and for the treatment of many gene-deficient brain...

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Detalles Bibliográficos
Autores principales: Lin, Kunzhang, Zhong, Xin, Li, Lei, Ying, Min, Yang, Tian, Zhang, Zhijian, He, Xiaobin, Xu, Fuqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556953/
https://www.ncbi.nlm.nih.gov/pubmed/33054827
http://dx.doi.org/10.1186/s13041-020-00679-1