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AAV9-Retro mediates efficient transduction with axon terminal absorption and blood–brain barrier transportation
Recombinant adeno-associated viruses (rAAVs), particularly those that permit efficient gene transfer to neurons from axonal terminals or across the blood–brain barrier, are useful vehicles for structural and functional studies of the neural circuit and for the treatment of many gene-deficient brain...
Autores principales: | Lin, Kunzhang, Zhong, Xin, Li, Lei, Ying, Min, Yang, Tian, Zhang, Zhijian, He, Xiaobin, Xu, Fuqiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556953/ https://www.ncbi.nlm.nih.gov/pubmed/33054827 http://dx.doi.org/10.1186/s13041-020-00679-1 |
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