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SMARCA4-Deficient Thoracic Sarcomatoid Tumors Represent Primarily Smoking-Related Undifferentiated Carcinomas Rather Than Primary Thoracic Sarcomas

INTRODUCTION: Highly aggressive thoracic neoplasms characterized by SMARCA4 (BRG1) deficiency and undifferentiated round cell or rhabdoid morphology have been recently described and proposed to represent thoracic sarcomas. However, it remains unclear whether such tumors may instead represent sarcoma...

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Detalles Bibliográficos
Autores principales: Rekhtman, Natasha, Montecalvo, Joseph, Chang, Jason C., Alex, Deepu, Ptashkin, Ryan N., Ai, Ni, Sauter, Jennifer L., Kezlarian, Brie, Jungbluth, Achim, Desmeules, Patrice, Beras, Amanda, Bishop, Justin A., Plodkowski, Andrew J., Gounder, Mrinal M., Schoenfeld, Adam J., Namakydoust, Azadeh, Li, Bob T., Rudin, Charles M., Riely, Gregory J., Jones, David R., Ladanyi, Marc, Travis, William D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7556987/
https://www.ncbi.nlm.nih.gov/pubmed/31751681
http://dx.doi.org/10.1016/j.jtho.2019.10.023