Poly(POG)n loaded with recombinant human bone morphogenetic protein-2 accelerates new bone formation in a critical-sized bone defect mouse model

BACKGROUND: Delivery of bone morphogenetic protein-2 (BMP-2) via animal-derived absorbable collagen materials is used for the treatment of large bone defects. However, the administration of bovine proteins to humans is associated with the risk of zoonotic complications. We therefore examined the eff...

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Detalles Bibliográficos
Autores principales: Tazawa, Ryo, Uchida, Kentaro, Minehara, Hiroaki, Matsuura, Terumasa, Kawamura, Tadashi, Sekiguchi, Hiroyuki, Muneshige, Kyoko, Inoue, Sho, Inoue, Gen, Takaso, Masashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557057/
https://www.ncbi.nlm.nih.gov/pubmed/33054796
http://dx.doi.org/10.1186/s13018-020-01977-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557057/
https://www.ncbi.nlm.nih.gov/pubmed/33054796
http://dx.doi.org/10.1186/s13018-020-01977-z

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