WRN modulates translation by influencing nuclear mRNA export in HeLa cancer cells

BACKGROUND: The Werner syndrome protein (WRN) belongs to the RecQ family of helicases and its loss of function results in the premature aging disease Werner syndrome (WS). We previously demonstrated that an early cellular change induced by WRN depletion is a posttranscriptional decrease in the level...

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Detalles Bibliográficos
Autores principales: Iglesias-Pedraz, Juan Manuel, Fossatti-Jara, Diego Matia, Valle-Riestra-Felice, Valeria, Cruz-Visalaya, Sergio Rafael, Ayala Felix, Jose Antonio, Comai, Lucio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557079/
https://www.ncbi.nlm.nih.gov/pubmed/33054770
http://dx.doi.org/10.1186/s12860-020-00315-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557079/
https://www.ncbi.nlm.nih.gov/pubmed/33054770
http://dx.doi.org/10.1186/s12860-020-00315-9

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