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WRN modulates translation by influencing nuclear mRNA export in HeLa cancer cells
BACKGROUND: The Werner syndrome protein (WRN) belongs to the RecQ family of helicases and its loss of function results in the premature aging disease Werner syndrome (WS). We previously demonstrated that an early cellular change induced by WRN depletion is a posttranscriptional decrease in the level...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557079/ https://www.ncbi.nlm.nih.gov/pubmed/33054770 http://dx.doi.org/10.1186/s12860-020-00315-9 |