Population structure and pharmacogenomic risk stratification in the United States

BACKGROUND: Pharmacogenomic (PGx) variants mediate how individuals respond to medication, and response differences among racial/ethnic groups have been attributed to patterns of PGx diversity. We hypothesized that genetic ancestry (GA) would provide higher resolution for stratifying PGx risk, since...

Descripción completa

Detalles Bibliográficos
Autores principales: Nagar, Shashwat Deepali, Conley, Andrew B., Jordan, I. King
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557099/
https://www.ncbi.nlm.nih.gov/pubmed/33050895
http://dx.doi.org/10.1186/s12915-020-00875-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557099/
https://www.ncbi.nlm.nih.gov/pubmed/33050895
http://dx.doi.org/10.1186/s12915-020-00875-4

Ejemplares similares