Cytotoxicity and Radiosensitizing Activity of the Fatty Acid Synthase Inhibitor C75 Is Enhanced by Blocking Fatty Acid Uptake in Prostate Cancer Cells

Prostate cancers, like many other types of cancer, express elevated levels of fatty acid synthase (FASN) to make more fatty acids, which are required for energy, signaling, and proliferation. Because inhibition of FASN has been shown to sensitize tumors to chemotherapy and radiation, we studied the...

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Detalles Bibliográficos
Autores principales: Rae, Colin, Fragkoulis, Georgios I., Chalmers, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Biology Contribution
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557210/
https://www.ncbi.nlm.nih.gov/pubmed/33083663
http://dx.doi.org/10.1016/j.adro.2020.06.022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557210/
https://www.ncbi.nlm.nih.gov/pubmed/33083663
http://dx.doi.org/10.1016/j.adro.2020.06.022

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