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Isonitriles: Versatile Handles for the Bioorthogonal Functionalization of Proteins

[Image: see text] The property of the isonitrile group to enable the simultaneous α-addition of a strong electrophile and a nucleophile has always attracted the attention of organic chemists. Its versatility is augmented when recognizing that its high structural compactness, the inertia to most of t...

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Detalles Bibliográficos
Autores principales: Méndez, Yanira, Vasco, Aldrin V., Humpierre, Ana R., Westermann, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2020
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557220/
https://www.ncbi.nlm.nih.gov/pubmed/33073077
http://dx.doi.org/10.1021/acsomega.0c03728