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MiR-146a rs2910164 G > C polymorphism modulates Notch-1/IL-6 signaling during infection: a possible risk factor for Crohn’s disease

BACKGROUND: MiR-146a, an effector mediator, targets Notch-1 and regulates the innate and adaptive immune systems response. Recently, we reported that Notch-1 signaling plays a key role in macrophage polarization and response during infection. We employed Mycobacterium avium paratuberculosis (MAP) in...

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Detalles Bibliográficos
Autores principales: Keewan, Esra’a, Naser, Saleh A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557229/
https://www.ncbi.nlm.nih.gov/pubmed/33072191
http://dx.doi.org/10.1186/s13099-020-00387-0