Verification of a Novel Approach to Predicting Effects of Antibiotic Combinations: In Vitro Dynamic Model Study with Daptomycin and Gentamicin against Staphylococcus aureus

To explore whether susceptibility testing with antibiotic combinations at pharmacokinetically derived concentration ratios is predictive of the antimicrobial effect, a Staphylococcus aureus strain was exposed to daptomycin and gentamicin alone or in combination in multiple dosing experiments. The su...

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Detalles Bibliográficos
Autores principales: Golikova, Maria V., Strukova, Elena N., Portnoy, Yury A., Zinner, Stephen H., Firsov, Alexander A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557373/
https://www.ncbi.nlm.nih.gov/pubmed/32854240
http://dx.doi.org/10.3390/antibiotics9090538

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557373/
https://www.ncbi.nlm.nih.gov/pubmed/32854240
http://dx.doi.org/10.3390/antibiotics9090538

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