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Verification of a Novel Approach to Predicting Effects of Antibiotic Combinations: In Vitro Dynamic Model Study with Daptomycin and Gentamicin against Staphylococcus aureus
To explore whether susceptibility testing with antibiotic combinations at pharmacokinetically derived concentration ratios is predictive of the antimicrobial effect, a Staphylococcus aureus strain was exposed to daptomycin and gentamicin alone or in combination in multiple dosing experiments. The su...
Autores principales: | Golikova, Maria V., Strukova, Elena N., Portnoy, Yury A., Zinner, Stephen H., Firsov, Alexander A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557373/ https://www.ncbi.nlm.nih.gov/pubmed/32854240 http://dx.doi.org/10.3390/antibiotics9090538 |
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