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Catechol Containing Polyelectrolyte Complex Nanoparticles as Local Drug Delivery System for Bortezomib at Bone Substitute Materials

The proteasome inhibitor bortezomib (BZM) is one of the most potent anti-cancer drugs in the therapy of multiple myeloma. In this study, an adhesive drug delivery system (DDS) for BZM was developed. Therefore, we extended the present DDS concept of polyelectrolyte complex (PEC) nanoparticle (NP) bas...

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Detalles Bibliográficos
Autores principales: Vehlow, David, Wong, Jeremy P. H., Urban, Birgit, Weißpflog, Janek, Gebert, Annett, Schumacher, Matthias, Gelinsky, Michael, Stamm, Manfred, Müller, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557399/
https://www.ncbi.nlm.nih.gov/pubmed/32847150
http://dx.doi.org/10.3390/pharmaceutics12090799