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Catechol Containing Polyelectrolyte Complex Nanoparticles as Local Drug Delivery System for Bortezomib at Bone Substitute Materials
The proteasome inhibitor bortezomib (BZM) is one of the most potent anti-cancer drugs in the therapy of multiple myeloma. In this study, an adhesive drug delivery system (DDS) for BZM was developed. Therefore, we extended the present DDS concept of polyelectrolyte complex (PEC) nanoparticle (NP) bas...
Autores principales: | Vehlow, David, Wong, Jeremy P. H., Urban, Birgit, Weißpflog, Janek, Gebert, Annett, Schumacher, Matthias, Gelinsky, Michael, Stamm, Manfred, Müller, Martin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557399/ https://www.ncbi.nlm.nih.gov/pubmed/32847150 http://dx.doi.org/10.3390/pharmaceutics12090799 |
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