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Evaluation of Nucleoside Analogs as Antimicrobials Targeting Unique Enzymes in Borrelia burgdorferi

The first line therapy for Lyme disease is treatment with doxycycline, amoxicillin, or cefuroxime. In endemic regions, the persistence of symptoms in many patients after completion of antibiotic treatment remains a major healthcare concern. The causative agent of Lyme disease is a spirochete, Borrel...

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Detalles Bibliográficos
Autores principales: Chakraborti, Monideep, Schlachter, Samantha, Primus, Shekerah, Wagner, Julie, Sweet, Brandi, Carr, Zoey, Cornell, Kenneth A., Parveen, Nikhat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557402/
https://www.ncbi.nlm.nih.gov/pubmed/32825529
http://dx.doi.org/10.3390/pathogens9090678