Repurposing Heparin as Antimalarial: Evaluation of Multiple Modifications Toward In Vivo Application

Heparin is a promising antimalarial drug due to its activity in inhibiting Plasmodium invasion of red blood cells and to the lack of resistance evolution by the parasite against it, but its potent anticoagulant activity is preventing the advance of heparin along the clinical pipeline. We have determ...

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Detalles Bibliográficos
Autores principales: Lantero, Elena, Aláez-Versón, Carlos Raúl, Romero, Pilar, Sierra, Teresa, Fernàndez-Busquets, Xavier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557421/
https://www.ncbi.nlm.nih.gov/pubmed/32872434
http://dx.doi.org/10.3390/pharmaceutics12090825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557421/
https://www.ncbi.nlm.nih.gov/pubmed/32872434
http://dx.doi.org/10.3390/pharmaceutics12090825

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