Tyrosine-Modification of Polypropylenimine (PPI) and Polyethylenimine (PEI) Strongly Improves Efficacy of siRNA-Mediated Gene Knockdown

The delivery of small interfering RNAs (siRNA) is an efficient method for gene silencing through the induction of RNA interference (RNAi). It critically relies, however, on efficient vehicles for siRNA formulation, for transfection in vitro as well as for their potential use in vivo. While polyethyl...

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Detalles Bibliográficos
Autores principales: Noske, Sandra, Karimov, Michael, Aigner, Achim, Ewe, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557430/
https://www.ncbi.nlm.nih.gov/pubmed/32927826
http://dx.doi.org/10.3390/nano10091809

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557430/
https://www.ncbi.nlm.nih.gov/pubmed/32927826
http://dx.doi.org/10.3390/nano10091809

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