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Repurposing Disulfiram (Tetraethylthiuram Disulfide) as a Potential Drug Candidate against Borrelia burgdorferi In Vitro and In Vivo

Lyme disease caused by the Borrelia burgdorferi (Bb or B. burgdorferi) is the most common vector-borne, multi-systemic disease in the USA. Although most Lyme disease patients can be cured with a course of the first line of antibiotic treatment, some patients are intolerant to currently available ant...

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Detalles Bibliográficos
Autores principales: Potula, Hari-Hara S. K., Shahryari, Jahanbanoo, Inayathullah, Mohammed, Malkovskiy, Andrey Victorovich, Kim, Kwang-Min, Rajadas, Jayakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557442/
https://www.ncbi.nlm.nih.gov/pubmed/32971817
http://dx.doi.org/10.3390/antibiotics9090633