L-Asparaginase Exerts Neuroprotective Effects in an SH-SY5Y-A53T Model of Parkinson’s Disease by Regulating Glutamine Metabolism

Background: Parkinson’s disease (PD) is the second most common neurodegenerative disease worldwide and involves deficiencies in alpha-synuclein (α-Syn) degradation. Effective therapeutic strategies for PD are urgently needed. L-asparaginase (L-ASNase) has been developed for therapeutic applications...

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Detalles Bibliográficos
Autores principales: Zhang, Qingxi, Gao, Yuyuan, Zhang, Jiahui, Li, You, Chen, Jianing, Huang, Rui, Ma, Guixian, Wang, Limin, Zhang, Yuhu, Nie, Kun, Wang, Lijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557534/
https://www.ncbi.nlm.nih.gov/pubmed/33117129
http://dx.doi.org/10.3389/fnmol.2020.563054

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557534/
https://www.ncbi.nlm.nih.gov/pubmed/33117129
http://dx.doi.org/10.3389/fnmol.2020.563054

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