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Cooperativity, absolute interaction, and algebraic optimization

We consider a measure of cooperativity based on the minimal interaction required to generate an observed titration behavior. We describe the corresponding algebraic optimization problem and show how it can be solved using the nonlinear algebra tool SCIP. Moreover, we compute the minimal interactions...

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Detalles Bibliográficos
Autores principales: Kaihnsa, Nidhi, Ren, Yue, Safey El Din, Mohab, Martini, Johannes W. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557646/
https://www.ncbi.nlm.nih.gov/pubmed/32968839
http://dx.doi.org/10.1007/s00285-020-01540-8