Inhibition of class I PI3K enhances chaperone-mediated autophagy

Chaperone-mediated autophagy (CMA) is the most selective form of lysosomal proteolysis, where individual peptides, recognized by a consensus motif, are translocated directly across the lysosomal membrane. CMA regulates the abundance of many disease-related proteins, with causative roles in neoplasia...

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Detalles Bibliográficos
Autores principales: Endicott, S. Joseph, Ziemba, Zachary J., Beckmann, Logan J., Boynton, Dennis N., Miller, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557678/
https://www.ncbi.nlm.nih.gov/pubmed/33048163
http://dx.doi.org/10.1083/jcb.202001031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557678/
https://www.ncbi.nlm.nih.gov/pubmed/33048163
http://dx.doi.org/10.1083/jcb.202001031

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