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Inhibition of class I PI3K enhances chaperone-mediated autophagy

Chaperone-mediated autophagy (CMA) is the most selective form of lysosomal proteolysis, where individual peptides, recognized by a consensus motif, are translocated directly across the lysosomal membrane. CMA regulates the abundance of many disease-related proteins, with causative roles in neoplasia...

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Detalles Bibliográficos
Autores principales:	Endicott, S. Joseph, Ziemba, Zachary J., Beckmann, Logan J., Boynton, Dennis N., Miller, Richard A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7557678/ https://www.ncbi.nlm.nih.gov/pubmed/33048163 http://dx.doi.org/10.1083/jcb.202001031

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